Understanding Listedness/Expectedness

By Drug Safety Hub

When you take a medication, have you ever wondered how doctors and scientists know what side effects to expect? That’s where the concept of Listedness/Expectedness comes into play in the field of Pharmacovigilance.

What is Listedness/Expectedness?

In simple terms, Listedness (or Expectedness) is a term used in pharmacovigilance to describe whether a specific adverse event is listed (expected) in the product information of a drug. If an event is not listed, it is considered unlisted (unexpected). It’s like a roadmap that guides us through the potential side effects of a drug.

Why is it Important?

The assessment of Listedness/Expectedness is crucial in pharmacovigilance. It helps in identifying new safety signals and updating the product information to include new potential risks. It’s like a detective, constantly on the lookout for new clues and information.

How is it Assessed?

The assessment of Listedness/Expectedness involves a detailed review of the product information, scientific literature, and data from clinical trials. It’s a meticulous process, requiring a keen eye for detail and a deep understanding of the drug and its effects.

Challenges in Assessment

Despite its importance, the assessment of Listedness/Expectedness is not without its challenges. The evolving nature of scientific knowledge, differences in product information across regions, and the subjective nature of the assessment can make it a complex task. But like any good challenge, it pushes the field of pharmacovigilance to constantly evolve and improve.

Future of Clinical Trials